CVE-2026-100845

HIGH
Published Sep 27, 2026 Modified Sep 30, 2026 CWE-502

Description

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

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CVSS v3.1 Score

7.8
HIGH
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

EPSS — Exploit Prediction

0.0014
Probability of exploitation
0.03%
Percentile rank

EPSS estimates the probability that this vulnerability will be exploited in the wild within the next 30 days. A higher score means more likely to be exploited.

Weakness Type (CWE)

CWE-502 Deserialization of Untrusted Data

Affected Products

Vendor Product
project-monai monai

References

Frequently Asked Questions

What is CVE-2026-100845? +
MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline. It has a CVSS v3.1 base score of 7.8 (HIGH).
How severe is CVE-2026-100845? +
CVE-2026-100845 has a CVSS v3.1 score of 7.8 out of 10, rated HIGH. This is a high-severity vulnerability that should be prioritized for patching. The EPSS score is 0.0014, placing it in the 0th percentile for exploitation probability.
What products are affected by CVE-2026-100845? +
CVE-2026-100845 affects products from project-monai, specifically: monai. Check the affected products table above for specific version ranges.
How do I check if I'm vulnerable to CVE-2026-100845? +
You can use Secably's free Website Scanner to check your website for known vulnerabilities. For infrastructure scanning, use the Port Scanner to identify exposed services that may be affected. Check the vendor advisories linked above for specific patch and version information.

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