CVE-2025-50675

HIGH
Published Aug 7, 2025 Modified Apr 15, 2026 CWE-732

Description

GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation.

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CVSS v3.1 Score

7.8
HIGH
CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H

Weakness Type (CWE)

CWE-732 CWE-732

References

Frequently Asked Questions

What is CVE-2025-50675? +
GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation. It has a CVSS v3.1 base score of 7.8 (HIGH).
How severe is CVE-2025-50675? +
CVE-2025-50675 has a CVSS v3.1 score of 7.8 out of 10, rated HIGH. This is a high-severity vulnerability that should be prioritized for patching.
How do I check if I'm vulnerable to CVE-2025-50675? +
You can use Secably's free Website Scanner to check your website for known vulnerabilities. For infrastructure scanning, use the Port Scanner to identify exposed services that may be affected. Check the vendor advisories linked above for specific patch and version information.

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